One of the biggest changes DX12 brings to the table is the increased reliance on developers to properly optimize their code for GPUs. Unlike DX11, there will have fewer levers to tweak in the GPU driver, with more work being needed in the game engine and the game itself. To address this, AMD has announced a partnership with multiple game engine and game developers to implement DX12.
To kick start the effort, AMD is headlining 5 games and engines they are partnering with to ensure DX12 works smoothly with Radeon GPUs with the software. These are Ashes of the Singularity by Stardock and Oxide Games, Total War: WARHAMMER by Creative Assembly, Battlezone VR by Rebellion, Deus Ex: Mankind Divided by Eidos-Montréal and the Nitrous Engine by Oxide Games. These titles span a wide range from RTS to RPG and FPS which gives a sense that AMD is trying to cast as wide a net as possible.
In addition to this, AMD will also be working with EA and Dice to get the Frostbite 3 engine to enable DX12. This engine is of particular importance due to the many AAA EA and other titles using it. AMD is also hoping to push Asynchronous Compute and to make sure games will squeeze the most out of GCN using DX12.